Methyl p-chlorocinnamate

Details

English name: Methyl p-chlorocinnamate

CAS No: 7560-44-3

Molecular formula: C10H9ClO2

Molecular weight: 196.5

Melting point: 78-81℃

Packing: 25kg Paper barrel

Assay: ≥99%

Quality: Enterprise standard

Physicochemical property: White Crystalline Powder, it can disolve in ethyl alcohol and diethyl ether, can't disolve in water.

Preparation method: Obtained by reacting chlorocinnamic acid with methanol in the presence of concentrated sulfuric acid.

Application: This product is an organic synthesis intermediate.

Storage condition: Seal in a cool, dry environment.

Stability: If used and stored according to specifications, it will not decompose.

 

Methyl p-chlorocinnamate is an organic chemical, often used in industry, pharmaceutical industry, etc., obtained by reacting chlorobenzaldehyde with acetic anhydride. The chlorobenzene formaldehyde, acetic anhydride and sodium acetate with reaction 13 h under 180 ℃. After the reaction, it is slightly cold. Pour into the water, filter and wash the filter cake with water. Dissolve the cake repeatedly with ammonia until only a small amount of brownish-yellow sticky remains remain. The ammonium salt solution was filtered, then the chlorocinnamic acid was precipitated out with 3N dilute sulfuric acid, and the product was filtered and dried.

 

Methyl p-chlorocinnamate is mainly used to synthesize methyl bromomethyl cinnamate from the upstream raw material of the antithrombotic agent ozagrel sodium. The methyl methylanilate was prepared by N- butyl diimide bromide bromide and the total yield was 67%.

 

Keywords: Methyl p-chlorocinnamate, p-chlorocinnamic acid, 1615-02-7, cinnamic acid

 

 

 

 

 

Specifications